3D Databases are an increasingly viable method for identification of novel molecular entities. They can be used for finding data as simple as the distance between a pair of atoms to complex data on Steric and electrostatic complementarity defined by a protein binding site. Representations of the molecules in databases have shifted from explicit definition of atoms to a more fuzzy atom type description. In theory, these more general atom types should have the effect of increasing the number of new classes of hits discovered via a 3D search.

Our team is experienced in the design of 3D databases - the design depends on the intended use and search strategy for the database.

• The database takes a 2D model of the structures and converts it to 3D. The source for the graphical and logical database is the same so rendering is quite accurate.
• All our databases are built to industry standards. This makes it easy to edit and refine them subsequently. Other rendering software can also be used to render the databases - there is no render platform dependence.
• The graphical databases are in multi levels of details (LOD), resulting in very fast real time performance. LOD is one of the features that can be configured by a resource file.